SSI DiagnosticaHerredsvejen 23400 HillerødDENMARKT: (+45) 48 29 91 00EAN: 5790 002327452VAT: 37294535
All virulent/pathogenic pneumococci produce a sugar capsule. This sugar capsule is unique and is found in more than 90 different variants. It is on the basis of these capsules that these serotypes are defined.
Streptococcus pneumoniae expresses a number of different sugars on the cell surface. Most sugars are in the cell capsule, which defines the more than 90 different pneumococcal serotypes currently known. In addition to the type-specific capsule sugars, all pneumococci also express a group antigen, referred to as the cell wall polysaccharide (CWPS). CWPS is found in two different forms, depending on the quantity of phosphorylcholine per sugar unit. The capsule sugars are found in existing vaccines, partly in conjugate vaccine for children, but also in pure sugar vaccines for adults.
Pneumococcal serotype specific capsule sugars are produced by purifying the sugar from well-defined reference strains. The protein and DNA/RNA impurity is minimal and less than 3% of the total quantity.
The pneumococcal capsules can be used in immunological investigations such as ELISA antibody assays, to evaluate whether any vaccination/revaccination is desirable.
SSI Diagnostica offers pneumococcal capsules from all the serotypes described.
SSI Diagnostica A/SHerredsvejen 23400 Hillerød
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Material safety data sheets